| 1S78_DC:A | 1L7I_HL | pertuzumab (Perjeta) | 2A91_A | ErbB2 | 1.13 | 2175.1 | Rigid | Y | 500 | -8.45 |
| 3MJ9_HL:A | 3MJ8_HL | HL4E10 | 3MJ6_A | JAML | 1.48 | 2456.6 | Rigid | Y | 8 | -11.05 |
| 3SE8_HL:G | 5JXA_HL | VRC03 | 3TGT_A | HIV 93TH057 gp120 | 1.22 | 2690.3 | Rigid | Y | | |
| 3U7Y_HL:G | 3U7W_HL | NIH45-46 | 3TGT_A | HIV 93TH057 gp120 | 0.84 | 2543.9 | Rigid | Y | 160 | -9.27 |
| 3WD5_HL:ABC | 4NYL_HL | adalimumab (Humira) | 1TNF_ABC | TNFalpha | 0.93 | 2328.2 | Rigid | Y | 0.115 | -13.56 |
| 4FP8_HL:A | 4FNL_HL | C05 | 4FNK_ABCDEF | influenza H3 HA | 0.34 | 1321.5 | Rigid | Y | 430 | -8.83 |
| 4M5Z_HL:A | 4M5Y_HL | 5J8 | 3UYX_A | influenza H1N1 HA1 | 0.73 | 1591.1 | Rigid | Y | 10 | -11.1 |
| 4Y7M_A:C | 4QGY_A | nb25 | 4Y7L_A | E coli TssM CTD | 0.84 | 1102.5 | Rigid | Y | 1.61 | -11.79 |
| 5GRJ_HL:A | 4NKI_HL | avelumab scFv (Bavencio) | 4Z18_A | PD-L1 | 1.14 | 1752.5 | Rigid | Y | 0.0421 | -14.15 |
| 5JMO_D:B | 5JMR_A | Nb14 | 5JXI_A | Furin | 0.29 | 1393.9 | Rigid | Y | | |
| 5O14_HL:A | 5UR8_AB | 1A12 | 3KVD_D | Neisseria meningitidis fHbp | 0.63 | 1523.7 | Rigid | Y | 0.019 | -14.62 |
| 5O1R_HL:A | 5NYX_HL | 5H2 | 6CUJ_A | Neisseria meningitidis NHBA | 0.9 | 1851.9 | Rigid | Y | | |
| 5SV3_C:D | 5SV4_A | A3C8 | 1IFT_A | Ricin | 0.57 | 1293.6 | Rigid | Y | 0.627 | -12.55 |
| 5WK3_WV:D | 5WK2_HL | M116 | 1NR4_A | CCL17 | 0.57 | 1222.3 | Rigid | Y | | |
| 5WUX_HL:EFG | 5WUV_HL | certolizumab (Cimzia) | 1TNF_CBA | TNFalpha | 0.8 | 2072.8 | Rigid | Y | 0.0274 | -14.41 |
| 5X0T_AB:E | 5X4G_AB | 6H8 | 3B5H_A | CD147 | 1.25 | 1316.2 | Rigid | Y | | |
| 5Y9J_HL:ABC | 5Y9K_HL | belimumab (Benlysta) | 1KXG_ABC | B lymphocyte stimulator | 0.96 | 1976.3 | Rigid | Y | 0.995 | -12.28 |
| 6A77_HL:A | 6A76_HL | B5209B | 5O5I_A | ROBO1 Ig5 | 0.95 | 1532.8 | Rigid | Y | | |
| 6B0S_HL:C | 6B0W_HL | 1710 Fab fragment | 3VDJ_A | circumsporozoite protein aTSR domain | 0.72 | 1353.2 | Rigid | Y | 178 | -9.11 |
| 6BPC_EF:D | 6BPB_AB | 4F7 | 5W53_A | Plasmodium vivax reticulocyte-binding protein 2b | 0.47 | 1644.5 | Rigid | Y | | |
| 6CWG_B:A | 6CWK_A | A9 | 1IFT_A | Ricin | 0.76 | 1151.2 | Rigid | Y | 0.1 | -13.64 |
| 6DBG_C:B | 6DBA_A | R303 | 1H6T_A | Listeria monocytogenes internalin B | 0.46 | 1525.2 | Rigid | Y | 0.15 | -13.4 |
| 6OC3_AB:F | 6OBZ_HL | FluA-20 | 6CHX_A | H1 hemagglutinin head | 0.59 | 1536.9 | Rigid | Y | | |
| 1AHW_AB:C | 1FGN_LH | Fab 5g9 | 1TFH_A | Tissue factor | 0.69 | 1899 | Rigid | | | -11.55 |
| 1DQJ_AB:C | 1DQQ_CD | Fab Hyhel63 | 3LZT_ | HEW lysozyme | 0.75 | 1765 | Rigid | | | -11.67 |
| 1E6J_HL:P | 1E6O_HL | Fab 13B5 | 1A43_ | HIV-1 capsid protein p24 | 1.05 | 1245 | Rigid | | | -10.28 |
| 1JPS_HL:T | 1JPT_HL | Fab D3H44 | 1TFH_B | Tissue factor | 0.51 | 1852 | Rigid | | | -13.64 |
| 1MLC_AB:E | 1MLB_AB | Fab44.1 | 3LZT_ | HEW lysozyme | 0.6 | 1392 | Rigid | | | -9.61 |
| 1VFB_AB:C | 1VFA_AB | Fv D1.3 | 8LYZ_ | HEW lysozyme | 1.02 | 1383 | Rigid | | | -11.46 |
| 1WEJ_HL:F | 1QBL_HL | Fab E8 | 1HRC_ | Cytochrome C | 0.31 | 1177 | Rigid | | | -12.48 |
| 2FD6_HL:U | 2FAT_HL | Plasminogen receptor antibody | 1YWH_A | Plasminogen activator receptor | 1.07 | 1139 | Rigid | | | |
| 2I25_N:L | 2I24_N | Shark single domain antigen receptor | 3LZT | Lysozyme | 1.21 | 1425 | Rigid | | | -12.28 |
| 2VIS_AB:C | 1GIG_LH | Fab HC19 | 2VIU_ACE | Flu virus hemagglutinin | 0.8 | 1296 | Rigid | | | -7.36 |
| 2VXT_HL:I | 2VXU_HL | Murine reference antibody 125-2H FAB | 1J0S_A(6) | Interleukin-18 | 1.32 | 2163 | Rigid | | 0.533 | -12.65 |
| 2W9E_HL:A | 2W9D_HL | ICSM 18 FAB fragment | 1QM1_A | Prion protein fragment | 1.13 | 1677 | Rigid | | 0.13 | -13.49 |
| 3EOA_LH:I | 3EO9_LH | Efalizumab FAB fragment | 3F74_A | Integrin alpha-L I domain | 0.39 | 1272 | Rigid | | 2.2 | -11.81 |
| 3HMX_LH:AB | 3HMW_LH | Ustekinumab FAB | 1F45_AB | Interleukin-12 | 0.73 | 1841 | Rigid | | | |
| 3MXW_LH:A | 3MXV_LH | Anti-Shh 5E1 chimera FAB fragment | 3M1N_A | Sonic Hedgehog N-terminal domain | 0.48 | 1696 | Rigid | | 7 | -11.31 |
| 3RVW_CD:A | 3RVT_CD | 4C1 FAB | 3F5V_A | DER P 1 allergen | 0.5 | 1383 | Rigid | | 19 | -10.53 |
| 4DN4_LH:M | 4DN3_LH | CNTO888 FAB | 1DOL_A | MCP-1 | 0.81 | 1317 | Rigid | | 0.038 | -14.22 |
| 4FQI_HL:ABEFCD | 4FQH_HL | CR9114 FAB | 2FK0_ABCDEF | H5N1 influenza virus hemagglutinin | 1.08 | 1459 | Rigid | | 0.9 | -12.55 |
| 4G6J_HL:A | 4G5Z_HL | Canakinumab antibody fragment | 4I1B_A | Interleukin-1 beta | 0.61 | 1893 | Rigid | | 4.1 | -11.44 |
| 4G6M_HL:A | 4G6K_HL | Gevokizumab antibody fragment | 4I1B_A | Interleukin-1 beta | 0.52 | 1673 | Rigid | | 0.29 | -13.01 |
| 4GXU_MN:ABEFCD | 4GXV_HL | 1F1 antibody | 1RUZ_HIJKLM | 1918 H1 Hemagglutinin | 0.78 | 1830 | Rigid | | 6.2 | -11.2 |
| 2DD8_HL:S | 2G75_AB | m396 | 2GHV_E | SARS spike | 2.19 | 1709.7 | Medium | Y | 20 | -10.5 |
| 3RJQ_B:A | 3R0M_A | A12 | 3TGR_A | C1086 HIV gp120 | 0.79 | 1734.4 | Medium | Y | | |
| 4ETQ_HL:C | 4EBQ_HL | LA5 | 4E9O_X | vaccinia D8L IMV | 0.47 | 2277.9 | Medium | Y | 0.18 | -13.29 |
| 4M3K_B:A | 4M3J_A | cAb-H7S | 4BLM_A | B. licheniformis beta-lactamase | 1.77 | 1588 | Medium | Y | | |
| 4POU_B:A | 4POY_A | VHHmetal | 6ETL_A | bovine RNase A | 1.83 | 1313.3 | Medium | Y | 157 | -9.28 |
| 5CBA_AB:E | 5C2B_HL | 3B4 scFv | 4ZAI_A | CXCL13 | 1.49 | 1790.2 | Medium | Y | 0.3715 | -13.38 |
| 5E5M_B:A | 5E03_A | H11 | 5E56_A | mouse CTLA-4 | 1.56 | 1341.4 | Medium | Y | | |
| 5HGG_T:A | 5HDO_A | Nb4 | 4FUD_A | uPA | 0.84 | 1969 | Medium | Y | 0.054 | -14.01 |
| 5HYS_CD:JK | 2XA8_HL | omalizumab (Xolair) | 4GT7_AB | IgE-Fc3-4 | 1 | 1331.6 | Medium | Y | 10 | -10.91 |
| 5KOV_C:AB | 5I30_HL | PL-2 scFv | 5KOU_AB | astrovirus 2 capsid protein spike domain | 1.69 | 1735 | Medium | Y | 1.87 | -11.91 |
| 5VNW_D:A | 5VNV_A | Nb.b201 | 1E78_A | human serum albumin | 1.49 | 966.8 | Medium | Y | 430 | -8.68 |
| 5WHK_HL:AB | 5WHJ_HL | DX-2507 | 5BXF_AB | FcRn-B2M | 1.88 | 1849.6 | Medium | Y | 1.81 | -11.93 |
| 6A0Z_HL:A | 6A0X_AB | 13D4 | 2FK0_A | H5N1 hemagglutinin head | 1.28 | 1660.7 | Medium | Y | 53 | -9.92 |
| 6AL0_HL:A | 4YNY_AB | NZ-1 | 6AKQ_A | A. aeolicus site-2 protease homolog with PA tag insertion | 1.89 | 1622.8 | Medium | Y | | |
| 6EY6_I:AB | 5FWO_A | nb130 | 6EY5_AB | P. gingivalis PorM | 1.9 | 1806.8 | Medium | Y | 8 | -11.05 |
| 3EO1_AB:CF | 3EO0_AB | GC-1008 FAB fragment | 1TGJ_AB | Transforming Growth Factor-Beta 3 | 1.37 | 1630 | Medium | | | |
| 3G6D_LH:A | 3G6A_LH | CNTO607 FAB | 1IK0_A(10) | Interleukin-13 | 1.86 | 1793 | Medium | | 0.0184 | -14.65 |
| 3HI6_XY:B | 3HI5_HL | AL-57 FAB fragment | 1MJN_A | Integrin alpha-L I domain | 1.65 | 1871 | Medium | | 4700 | -7.27 |
| 3L5W_LH:I | 3L7E_LH | C836 FAB | 1IK0_A(11) | Interleukin-13 | 0.48 | 1138 | Medium | | 0.54 | -14.01 |
| 3V6Z_AB:F | 3V6F_AB | FAB E6 | 3KXS_F | Capsid protein assembly domain | 1.82 | 1922 | Medium | | 3.3 | -11.57 |
| 2FJG_HL:VW | 2FJF_HL | G6 | 4KZN_AB | VEGF | 2.51 | 1678.2 | Difficult | Y | 20 | -10.92 |
| 4DW2_HL:U | 4DVB_AB | mAb-112 | 4DVA_U | uPA | 2.27 | 2037.6 | Difficult | Y | | |
| 5C7X_HL:A | 5D7S_HL | MOR04357 | 2GMF_A | GM-CSF | 2.31 | 2523.3 | Difficult | Y | 0.007 | -15.22 |